Clinventive is a clinical data consultancy and software practice: CDISC standards strategy, SDTM/ADaM specification and programming, CORE conformance, and synthetic study data — home of the Verdatic platform.
Standards governance, version management, therapeutic-area rollout, and standards-team buildout — from first SDTM adoption to mature, governed catalogs.
Mapping specifications, value-level metadata, Define-XML, and production programming in SAS, R, or Python — submission-ready datasets and the documentation to match.
In Verdatic: mapping from raw data →CORE engine adoption, rule triage, and findings-disposition workflows — guided by someone who helped author the rule set the engine runs.
Verdatic's trust & validation page →Realistic, standards-aligned synthetic subjects for development, testing, and training — coherent across visits, domains, and treatment arms. Powered by Verdatic.
In Verdatic: modeling treatment effects →Clean data for PASS cases and deliberately dirty twins for FAIL cases, generated from your own edit checks — automated UAT for study builds before first patient in.
In Verdatic: UAT end to end →Masking plans for potentially unblinding data — candidate identification, rule authoring, leak analysis, and audited execution, in the engine or as portable SAS, R, and Python programs.
In Verdatic: masking from plan to proof →Also available: clinical data systems advisory, fractional standards leadership, and team mentoring.
Everything the consultancy does by hand, Verdatic does as software: it simulates realistic study data from your design, checks its quality against CDISC CORE, and generates the SAS, R, and Python programs your team will run when real data arrives. Verdatic is an entrant in the 2026 CDISC AI Innovation Challenge.
Verdatic generates synthetic data for development, testing, training, and demonstration — not regulatory submission.
Essays on standards, simulation, and the sensible use of AI in clinical data — the first piece is live.
Revisiting the 2019 Interchange paper — what held up, and what was underestimated.
From hand-typed test patients to learned, coherent simulation — what changed, and why now.
From founding the SDS Conformance Rules team to CORE-in-the-loop — an insider's arc.
Clinventive is led by W. Stetson Line — founder of the CDISC SDS Conformance Rules team (precursor of today's CDISC CORE), recipient of CDISC's 2017 award for Outstanding Contributions to Standards Development, and creator of Verdatic, with ten U.S. patent applications pending on the platform's methods.
Engagements, questions, or a Verdatic walkthrough with your own study design.